Georgios Vizyinos possessed a solid scientific background in psychology, which, together with his artistic, literary talent, led him to initiate the genre of psychological realism in Greek literature and to improve prose writing. The bulk of his creative work consists of six novels (all published between 1883 and 1884,) a few poems, one diatribe, and his stories for children.
He attributed psychological depth and critical realism to Greek ethography, avoiding ridicule and idealization. He was the first author to make children the central point in his work.
He was committed to a psychiatric hospital in 1892 and died in 1896, the year of the first modern Olympic games.